CLINICAL RESEARCH

The CCRUM’s clinical research programme is designed for critical appraisal of the theory of pathogenesis, symptomatology,clinical methods of diagnosis and prognosis, principles, line and methods of treatment enunciated in the classical texts of Unani Medicine. The programme is aimed at evaluating the efficacy and safety of Unani drugs and developing medicinally beneficial remedies by integrating contemporary diagnostic methods and aligning them with rigorous scientific standards. Under this programme, the NRIUMSD conducts clinical studies on common diseases and chronic ailments of national importance, to provide safe and effective Unani treatments for these diseases. The primary objectives of the programme are as follows: To verify the claims and perceptions reported in classical texts of Unani Medicine in respect of the diseases and their remedies. To validate the assertions and insights documented in classical literature of Unani Medicine pertaining to various diseases and their corresponding remedies. To harmonize traditional wisdom with contemporary scientific methodology to establish Unani Medicine as a viable alternative in healthcare delivery. To investigate the consistency and acceptability of Unani formulations, analyzing both their beneficial and adverse effects. To evaluate the safety and toxicity profiles of Unani drugs, while assessing their overall acceptance as a therapeutic approach.
Under this programme, the institute has established therapeutic efficacy of Unani drugs in some chronic and common diseases, such as Baraṣ (vitiligo), Iltihāb Tajāwīf al-Anf (sinusitis), Iltihāb al-Kabid (viral hepatitis), Kathrat Shaḥm al-Dam (hyperlipidaemia), Dhubḥa Ṣadriyya Muzmin (chronic stable angina), Dhayābīṭus Sukkarī (diabetes mellitus), Ḍaghṭ al-Dam Qawī Lāzimī (essential hypertension) and Sayalān al-Raḥim (leucorrhoea). Besides, studies on immunomodulatory effects of some Unani drugs as health and vitality promoters among the elderly have been undertaken. In these diseases, the institute has not only been able to develop effective drugs, but also establish standard operating procedures (SOPs) for their treatment. Efficacy of Unani regimenal therapy, namely Munḍij and Mushil (concoctive and purgative) therapy, has also been validated scientifically and adopted as line of treatment as mentioned in the Unani classics. Besides, clinical validation of the safety and efficacy of Unani pharmacopoeial formulations has also been continued since the year 2012.